Replacement of clopidogrel with ticagrelor for a patient with polycythemia vera accompanied by repeated myocardial infarction and acute stent thrombosis

Polycythemia vera (PV) is a clonal disorder arising in multipotent hematopoietic progenitor cells. It causes the overproduction of red cells and, to a lesser extent, neutrophils and platelets. PV occurs with a slight predominance in men, and the median age of diagnosis is 60 years [1]. Although the association between PV and coronary artery disease is unknown, previous studies have reported coronary events occurring during the course of PV [2].